Crystal structure of PAK1 in complex with an inhibitor compound G-5555
收藏Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal structure of PAK1 in complex with an inhibitor compound G-5555 Descriptor: 8-[(trans-5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one, Serine/threonine-protein kinase PAK 1 Authors: Oh, A, Tam, C, Wang, W. Deposit date: 2015-08-26 Release date: 2016-01-27 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety. Acs Med.Chem.Lett., 6, 2015
创建时间：
2015-08-26
