A Double-blind, Randomized Controlled Trial of Probiotic Intervention in Patients with Clinically Diagnosed Depression: A Pilot Study

This thesis evaluates the preliminary efficacy and feasibility of probiotics intervention in patients with clinically diagnosed depression. We present a pioneering probiotics study in a Malaysian setting involving patients with clinically diagnosed depression that demonstrates a feasible methodological approach and supports the progressive expansion of probiotics as a potential stand-alone therapeutic within the clinical management of patients with mild MDD and as a preventive intervention for individuals at risk of developing depressive disorder.