UCKL1 phosphorylates urindine, cytidine
收藏reactome.org2025-01-08 收录
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Based on sequence similarity, cytosolic uridine-cytidine kinase-like 1 (UCKL1 aka F538) is thought to function as a novel human uridine kinase/uracil phosphoribosyltransferase (Kashuba et al. 2002). The two human uridine kinases 1 and 2 (UCK1 and UCK2) characterised to date phosphorylate uridine/cytidine to uridine monophosphate (UMP)/cytidine monophosphate (CMP) using ATP as a phosphate donor (Greenberg et al. 1977, Van Rompay et al. 2001).
基于序列相似性,细胞质尿苷-胞苷激酶样1(UCKL1,又称F538)被认为作为一种新型的人类尿苷激酶/尿苷磷酸核糖基转移酶(Kashuba 等人,2002年)发挥作用。截至目前,所鉴定的人类尿苷激酶1和2(UCK1和UCK2)能够通过使用ATP作为磷酸供体,将尿苷/胞苷磷酸化为尿苷单磷酸(UMP)/胞苷单磷酸(CMP)(Greenberg 等人,1977年,Van Rompay 等人,2001年)。
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