Consistency of three clustering methods with EC assignments

aTotal proteome size = 112,920.bEnzyme groups are defined as groups with at least two proteins for which EC annotation is available.cA total of 4,739 proteins have EC annotations according to ENZYME database.dAll EC-annotated proteins in the group have the same or consistent EC numbers. Percentages indicate fraction of enzyme groups which are consistent in EC annotation, or fraction of EC-annotated proteins properly put into consistent groups.