Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor
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Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor Descriptor: 5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE, Poly [ADP-ribose] polymerase-1 Authors: Kinoshita, T. Deposit date: 2003-08-14 Release date: 2004-09-14 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (3 Å) Cite: Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase J.Med.Chem., 47, 2004
创建时间：
2003-08-14
