Tumor genomic profiling of Vietnamese colorectal cancer patients

In Vietnam, CRC accounts for 9.0% of all cancer cases in both women and men, with 16,426 new cases and 8,203 deaths in 2020. However, the mutational landscape of CRC in Vietnam and its translational potential for precision medicine are currently unknown. In this study, we used NGS to provide the first somatic variant landscape of the Vietnamese CRC patients that contributes to the knowledge base of the genetic complexity of colorectal cancer.