Chromatin immunoprecipitation of REH cells was performed using fractionation-assisted native chromatin immunoprecipitation method.Specific antibodies for MLL, ENL, H3K27ac, MOZ, RNA2 non-p, and RNAP2
ChIP-seq of H3K4me2, H3K9me2, and H3K27me3 was performed in YB5 cells to determine the impact of baseline histone methylation patterns on gene reactivation by epigenetic therapy Biological duplicates
Cells adapt to environmental changes, including fluctuations in oxygen levels, through the induction of specific gene expression programs. To identify genes regulated by hypoxia at the transcriptional