Cryo-EM structures and computational analysis for enhanced potency in MTA-synergic inhibition of human protein arginine methyltransferase 5
收藏Protein Data Bank Japan2024-06-12 更新2026-04-25 收录
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Cryo-EM structures and computational analysis for enhanced potency in MTA-synergic inhibition of human protein arginine methyltransferase 5 Descriptor: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Methylosome protein 50, N-[(2-aminoquinolin-7-yl)methyl]-9-(2-hydroxyethyl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide, ... Authors: Yadav, G.P, Wei, Z, Xiaozhi, Y, Chenglong, L, Jiang, Q. Deposit date: 2022-05-23 Release date: 2023-04-12 Last modified: 2024-06-12 Method: ELECTRON MICROSCOPY (3.14 Å) Cite: Cryo-EM structure-based selection of computed ligand poses enables design of MTA-synergic PRMT5 inhibitors of better potency. Commun Biol, 5, 2022
创建时间：
2022-05-23
