Genetic liability to hip fracture is associated with changes of serum testosterone and SHBG levels: A two-sample Mendelian Randomization Study

This study addressed uncertainties regarding the relationships between total testosterone (TT), bioavailable testosterone (BT), estradiol, sex hormone binding globulin (SHBG), and the risk of hip fracture (HF) through a comprehensive two-sample MR study, revealing potential causal links between these factors and hip fracture.