Understanding prostate cancer onset and progression in order to rationally treat this disease has been critically limited by a dire lack of relevant pre-clinical animal models. We have generated a set

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Development of a novel allograft model of prostate cancer: a new tool to inform clinical translation. Development of a novel allograft model of prostate cancer: a new tool to inform clinical translation

前列腺癌动物模型

放疗响应研究

This study presents a novel allograft model of high-risk, localised PCa. In characterising this model we have focused on its response to radiotherapy (RT). Overall design: The DVL3 cell line was deriv

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RNA seq analysis of primary tumors and metastases from the NPK (Nkx3.1CreERT2/+; Ptenflox/flox; KrasLSL-G12D/+; R26R-CAG-LSL-EYFP/+) prostate cancer mouse model. RNA seq analysis of primary tumors and metastases from the NPK (Nkx3.1CreERT2/+; Ptenflox/flox; KrasLSL-G12D/+; R26R-CAG-LSL-EYFP/+) prostate cancer mouse model

前列腺癌动物模型

肿瘤转录组学

Transcriptome analysis of lineage-marked prostate primary tumors and metastases from the NPK mouse model (Nkx3.1CreERT2/+; Ptenflox/flox; KrasLSL-G12D/+; R26R-CAG-LSL-EYFP/+) Overall design: Male mice

NIAID Data Ecosystem60

Histopathological analysis (most severe lesion) of individual prostate lobes in 8-, 12-, 16-, and 20-week-old C57BL/6 TRAMP x FVB mice 1 , 2 .

前列腺癌动物模型

组织学分析

Histopathological analysis (most severe lesion) of individual prostate lobes in 8-, 12-, 16-, and 20-week-old C57BL/6 TRAMP x FVB mice1, 2.

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