Transcriptome analysis in HBZ-transgenic/IL-6 knockout mice
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下载链接：
https://www.ncbi.nlm.nih.gov/sra/DRP006148
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资源简介：
A viral gene, HTLV-1 bZIP factor (HBZ), triggers systemic inflammation and T-cell lymphoma in transgenic mice. Here we show that loss of IL-6 accelerated inflammation and lymphomagenesis in HBZ transgenic mice. To understand the molecular mechanisms for the acceleration of inflammation and oncogenesis in HBZ-Tg/IL-6 KO mice, we performed RNA-seq analysis using splenic CD4+ T cells from 4 strains: WT, HBZ-Tg, IL-6 KO, and HBZ-Tg/IL-6 KO.
创建时间：
2020-06-04
