Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with compound 27
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6p05
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资源简介：
Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with compound 27 Descriptor: Bromodomain-containing protein 4, GLYCEROL, N-{1-[1,1-di(pyridin-2-yl)ethyl]-6-(1-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-3-yl)-1H-indol-4-yl}ethanesulfonamide Authors: Ratia, K.M, Xiong, R, Li, Y, Zhao, J, Gutgesell, L.M, Shen, Z, Dye, K, Dubrovyskyii, O, Zhao, H, Huang, F, Tonetti, D.A, Thatcher, G.R. Deposit date: 2019-05-16 Release date: 2020-05-20 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.54 Å) Cite: Novel Pyrrolopyridone Bromodomain and Extra-Terminal Motif (BET) Inhibitors Effective in Endocrine-Resistant ER+ Breast Cancer with Acquired Resistance to Fulvestrant and Palbociclib. J.Med.Chem., 63, 2020
创建时间：
2019-05-16
