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Structure of human O-GlcNAc hydrolase with new iminocyclitol type inhibitor

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5m7u
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Structure of human O-GlcNAc hydrolase with new iminocyclitol type inhibitor Descriptor: 2-[(2~{R},3~{S},4~{R},5~{R})-5-(hydroxymethyl)-3,4-bis(oxidanyl)-1-[3-[3-(trifluoromethyl)phenyl]propyl]pyrrolidin-2-yl]-~{N}-methyl-ethanamide, Protein O-GlcNAcase Authors: Roth, C, Chan, S, Offen, W.A, Hemsworth, G.R, Willems, L.I, King, D, Varghese, V, Britton, R, Vocadlo, D.J, Davies, G.J. Deposit date: 2016-10-28 Release date: 2017-03-29 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structural and functional insight into human O-GlcNAcase. Nat. Chem. Biol., 13, 2017
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2016-10-28
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