Cryo-EM structure of human gamma-secretase in complex with Abeta46

Cryo-EM structure of human gamma-secretase in complex with Abeta46 Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y. Deposit date: 2023-11-16 Release date: 2024-05-29 Last modified: 2025-07-23 Method: ELECTRON MICROSCOPY (3 Å) Cite: Molecular mechanism of substrate recognition and cleavage by human gamma-secretase. Science, 384, 2024