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Longitudinal analysis of developing neointimal vascular proliferation and pulmonary hypertension in rats

ChEBI2010-06-05 更新2026-07-21 收录

肺动脉高压动物模型

血管增生病理研究

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-843 数据链接链接失效反馈

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资源简介：

Longitudinal analysis of developing neointimal vascular proliferation and pulmonary hypertension in rats

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创建时间：

2010-06-05

肺动脉高压动物模型

激酶抑制剂药效评估

Pulmonary hypertension (PH) and cancer pathophysiology share common signal transduction pathways leading to abnormal endothelial and smooth muscle cell interactions and angioproliferative vasculopathy

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Reversible and irreversible PAH in a rat model for MCT+Shunt-induced PAH and hemodynamic unloading.

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PAH was induced by 60mg/kg MCT and an aorto-caval shunt. At different timepoints of PAH progression (day 14, 21 and 28 after MCT-injection), the left lung with PAH was hemodynamically unloading by uni

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Data_Sheet_1_Expression of a Human Caveolin-1 Mutation in Mice Drives Inflammatory and Metabolic Defect-Associated Pulmonary Arterial Hypertension.pdf

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Background: In 2012, mutations in Cav1 were found to be the driving mutation in several cases of heritable pulmonary arterial hypertension (PAH). These mutations replaced the last 21 amino acids of Ca

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The Effects of Complement in a Chronic Murine Model of Inflammatory Erosive Arthritis and Pulmonary Vascular Disease

关节炎免疫机制

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Dysfunction of the complement pathway contributes to diseases such rheumatoid arthritis (RA) and pulmonary hypertension (PH). Here we aim to determine whether complement deficiency has a protective ef

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Therapeutic benefits of intravenous cardiosphere-derived cell therapy in rats with pulmonary hypertension

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Pulmonary arterial hypertension (PAH) is a progressive condition characterized by occlusive pulmonary arteriopathy, in which survival remains poor despite pharmacologic advances. The aim of this study

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Longitudinal analysis of developing neointimal vascular proliferation and pulmonary hypertension in rats

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