Prediction of putative resistance islands in a carbapenem - resistant Acinetobacter baumannii global clone 2 clinical isolate. Acinetobacter baumannii strain:YU-R612

The YU-R612 genome consisted of a circular chromosome (ca. 4,075 kb) and two plasmids (ca. 74 kb and 5kb). Its sequence type (ST) under the Oxford scheme was ST191, consistent with assignment to GC2. ResFinder analysis showed that YU-R612 possessed the following resistance genes: four β-lactamase genes blaADC-25, blaOXA-66, blaOXA-23 and blaTEM-1; armA, aadA1, and aacA4 as aminoglycoside resistance-encoding genes; aac(6')Ib-cr for fluoroquinolone resistance; msr(E) for macrolide, lincosamide, and streptogramin B resistance; catB8 for phenicol resistance; and sul1 for sulfonamide resistance. By GIPSy analysis, six putative resistant islands (PRI) were determined on the YU-R612 chromosome. Among them, PRI1 possessed two copies of Tn2009 carrying the blaOXA-23 gene and PRI5 carried two copies of a class I integron carrying the sul1 and armA resistance genes.