fumarate + H2O <=> malate

Mitochondrial FH (fumarate hydratase) catalyzes the reversible reaction of fumarate and H2O to form malate. No chicken enzyme capable of catalyzing this reaction has been identified, although an open reading frame capable of encoding a protein closely similar to authentic human mitochondrial FH has been identified computationally in the ENSEMBL chicken gene set. This reaction is inferred from its human counterpart.

线粒体富马酸水合酶（fumarate hydratase，FH）催化富马酸与水（H2O）的可逆反应生成苹果酸。尽管在鸡中尚未发现能够催化此反应的酶，但通过计算分析，在ENSEMBL鸡基因集中已鉴定出一个开放阅读框，其编码的蛋白质与人类真实的线粒体FH高度相似。该反应的推断基于其人类同源反应。

搜集汇总

背景与挑战

背景概述

该数据集描述了三羧酸循环中延胡索酸与水反应生成苹果酸的可逆酶促反应，聚焦于鸡物种。数据集基于人类对应反应推断，鸡物种中尚未实验鉴定出延胡索酸水合酶，但计算预测存在相关基因。反应发生在线粒体基质中，涉及代谢途径的关键步骤。