Assessing completeness of cancer family history in EHRs using genetically-defined kinships: a cross-sectional study

The data in this submission is intended to allow others to replicate the results reported in our study article “Assessing completeness of cancer family history in EHRs using genetically-defined kinships: a cross-sectional study,” published in Genetics in Medicine Open in 2025. In this study, we leveraged genetic data from the Healthy Nevada Project to identify patients at Renown Health (a large regional hospital in Reno, Nevada) who were related by blood. We then examined the electronic health records of patients with cancer-affected blood-relatives to see whether their relatives’ cancer type was successfully documented in the patient’s family history record. Across all cancer types, 45.2% (95% confidence interval: 42.0-48.4%) of cancers were successfully documented.

Here we provide the data and R code used to fit the generalized estimating equations used to produce the key results in our study. If additional data is desired, please see the data availability statement included with our study article for details on access criteria.