Oncogenic calreticulin induces TGF-β expression and Treg expansion in the bone marrow microenvironment as a mechanism of immune escape
收藏NIAID Data Ecosystem2026-05-02 收录
下载链接：
https://zenodo.org/record/11311826
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资源简介：
This repository contains all necessary scRNA-seq inputs to reproduce the results described in "Oncogenic calreticulin induces TGF-β expression and Treg expansion in the bone marrow microenvironment as a mechanism of immune escape" by Schmidt et al. (Cancer Research 2024).
Content:
"MPN_calreticulin_bm.R" --> R script containing all code
"cells_table.RDS" --> cells table containing, cell_id, UMAP coordinates, complexity, cell type annotation and metadata
"normalized_matrix.RDS" --> quality control filtered, log2-normalized and centered expression matrix
"reference_signatures.RDS" --> all external signatures used for this study
"EV2_*", "EV5_*", "MPN2_*", "MPN5_*", --> cellranger outputs
创建时间：
2024-05-26
