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Crystal structures of FabI from F. tularensis in complex with novel inhibitors based on the benzimidazole scaffold

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4j1n
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Crystal structures of FabI from F. tularensis in complex with novel inhibitors based on the benzimidazole scaffold Descriptor: 1-(4-methoxy-3-methylbenzyl)-1,5,6,7-tetrahydroindeno[5,6-d]imidazole, Enoyl-[acyl-carrier-protein] reductase [NADH], GLYCEROL, ... Authors: Mehboob, S, Boci, T, Brubaker, L, Santarsiero, B.D, Johnson, M.E. Deposit date: 2013-02-01 Release date: 2014-07-23 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.45 Å) Cite: Structural and biological evaluation of a novel series of benzimidazole inhibitors of Francisella tularensis enoyl-ACP reductase (FabI). Bioorg.Med.Chem.Lett., 25, 2015
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2013-02-01
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