Additional file 9 of Sex specific molecular networks and key drivers of Alzheimer’s disease

Additional file 9: Supplemental Table 9. Modular differential connectivity analysis of male and female specific co-expression networks. MDC was calculated as the ratio of the mean module connectivity in one network to that for the same set of genes in another network. FDRs were calculated by two methods, sample-based permutation and gene-based permutation. The greater one of the two FDRs for each gene was taken as the final FDR for MDC of a module. The MDC analysis of A) female AD network modules versus male network in the PHG of the MSBB cohort, B) male AD network modules versus female network in the PHG of the MSBB cohort, C) female AD network modules versus male network in the PFC of the ROSMAP cohort, D) male AD network modules versus female network in the PFC of the ROSMAP cohort.