Crystal structure of FGFR4 kinase domain in complex with a covalent inhibitor
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Crystal structure of FGFR4 kinase domain in complex with a covalent inhibitor Descriptor: Fibroblast growth factor receptor 4, N-({4-[4-amino-3-(3,5-dimethyl-1-benzofuran-2-yl)-7-oxo-6,7-dihydro-2H-pyrazolo[3,4-d]pyridazin-2-yl]phenyl}methyl)prop-2-enamide Authors: Xu, Y, Liu, Q. Deposit date: 2018-11-29 Release date: 2019-10-23 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery and Development of a Series of Pyrazolo[3,4-d]pyridazinone Compounds as the Novel Covalent Fibroblast Growth Factor Receptor Inhibitors by the Rational Drug Design. J.Med.Chem., 62, 2019
创建时间：
2018-11-29
