Gene expression profiles of primary samples of acute myeloid leukemia (AML)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE110087
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资源简介：
As part of a clinical trial of the MDM2 inhibitor DS-3032b, 41 primary tumor samples were obtained before treatment from 38 patients newly diagnosed with AML, or relapsed or refractory to standard induction chemotherapy Gene expression features of pretreatment samples, along with TP53 mutation status, were found to correlate with clinical response to DS-3032b (manuscript under review). Gene expression profiles were determined using Affymetrix U133_2.0 arrays. Random forest analysis with cross validation was used to identify features correlating with clinical response. Clinical details for the samples will be provided in a Supplemental Table in the accompanying publication.
创建时间：
2019-03-25
