Estimated relative fitness deficit f(q) of mutations present in the genetic background of baseline isolates #1,#2/3,#4,#5.

A small value (close to 0) denotes a large fitness loss, whereas a value close to 1 denotes no fitness deficit. Values indicated are medians of all parameter estimates. The 5th and 95th percentile of estimates are indicated in brackets. 'n.ds’ means ‘not deselected’ and n.i. means parameter ‘not identifiable’. Parameters f(67S), f(208H), f(35I) and f(210W/211K) could not be reliably estimated from the data or were not significantly different from the value 1.