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Double mutant Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS-K1, C59R+S108N) complexed with Trimethoprim (TOP), NADPH and dUMP

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Protein Data Bank Japan2023-11-29 更新2026-04-19 收录
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https://pdbj.org/mine/summary/7f3z
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Double mutant Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS-K1, C59R+S108N) complexed with Trimethoprim (TOP), NADPH and dUMP Descriptor: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, Bifunctional dihydrofolate reductase-thymidylate synthase, GLYCEROL, ... Authors: Vanichtanankul, J, Tanramluk, D, Chitnumsub, P, Yuvaniyama, J, Yuthavong, Y. Deposit date: 2021-06-17 Release date: 2021-09-22 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.6 Å) Cite: MANORAA: A machine learning platform to guide protein-ligand design by anchors and influential distances. Structure, 30, 2022
创建时间:
2021-06-17
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