IRGM haplotype associations (8 polymorphisms).

EUAM, Euro-American lineages of Mycobacterium tuberculosis; del, deletion; rep, repeat (number of tetranucleotide repeats given in digits; see also Figure 1); OR, odds ratio; CI, 95% confidence interval; Pnom, nominal P value; WT, wild-type; DEL, 20.1 kb deletion. P values refer to comparisons of one haplotype to all other combinations and are adjusted for age, gender and ethnicity. Corrected global P value in cases caused by EUAM infections after 10000 permutations = 0.02. Missing genotypes are compensated for by simulations of all possible completions of the data.