Tyrosine phosphorylation of CARM1 promotes its enzymatic activity and alters its target specificity
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE200973
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CARM1 Y149F, Y334F or Y149F/Y334F mutants have decreased activtiy to dimethylate RUNX1. CARM1 Y149F, Y334F or Y149F/Y334F mutations were introduced into HEL cells. ChIP-seq analyses for RUNX1 and RUNX1 R319me2a were performed in wild type and CAMR1 mutant HEL cells.
创建时间:
2024-05-17



