five

Neuroprotective effect of CrAT overexpression in mice RGC

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE289014
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AAV2-CrAT prevent RGC loss against optic nerve crush and NMDA injury. in vitro study demonstrated that CrAT overexpression could prevent ferroptosis in oxidative stress in neuronal cells. We performed AAV2-CrAT intravitreal injection, and optic nerve crush in mice one month later after AAV2 injection. RGC was purified by FACS and gene expression changing was examined (duplicate).
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2025-09-30
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