Crystal structure of human p38 alpha complexed with a pyrimidinone compound
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Crystal structure of human p38 alpha complexed with a pyrimidinone compound Descriptor: 3-{5-chloro-4-[(2,4-difluorobenzyl)oxy]-6-oxopyrimidin-1(6H)-yl}-N-(2-hydroxyethyl)-4-methylbenzamide, 4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, Mitogen-activated protein kinase 14 Authors: Shieh, H.-S, Xing, L. Deposit date: 2011-04-25 Release date: 2011-06-15 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Substituted N-aryl-6-pyrimidinones: A new class of potent, selective, and orally active p38 MAP kinase inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
创建时间：
2011-04-25
