Depletion of UCEs from pooled classicalCNVs is robust to the species used to define UCEs.

HMR-HDM-HC: 896 UCEs representing the union of Human-Mouse-Rat, Human-Dog-Mouse, and Human-Chicken UCEs [2]. DMR: 527 Dog-Mouse-Rat UCEs. CoDHo: 1,696 Cow-Dog-Horse UCEs. HMR: 481 Human-Mouse-Rat UCEs. Proportion: of 1,000 expected overlap iterations, the number of times the expected overlap generated was equal to, or more extreme than, the observed UCE overlap (bp), divided by the total number of iterations, which was always 1,000. P-value: significance of whether the observed overlap (bp) differs from the expected overlaps, as determined by a Z-test. obs/exp: observed overlap (bp) divided by mean of expected overlaps (bp). Outcome: determined with a one-tailed test (α = 0.05).Depletion of UCEs from pooled classicalCNVs is robust to the species used to define UCEs.