Biased Expression of the FOXP3?3 Isoform in Aggressive Bladder Cancer Mediates Differentiation and Cisplatin Chemotherapy Resistance
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https://www.ncbi.nlm.nih.gov/sra/SRP074426
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This study shows for the first time that the FOXP3?3 isoform is preferentially expressed in bladder cancer and induces a more aggressive and luminal isoform is preferentially expressed in bladder cancer and induces a more aggressive and luminal regulation of cancer differentiation and the plasticity amongst cancer subtypes which can be leveraged to optimize therapeutic regimens. These findings also identify a novel molecular marker as a putative companion diagnostic to guide therapy and target to undermine chemotherapy resistance. Overall design: examination of RNA-Seq in two bladder cancer cell lines
创建时间：
2023-01-11
