five

Gata3 controls stem/progenitor maintenance potential in prostate organoids

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干细胞与再生医学数据中心2022-02-20 更新2024-03-06 收录
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http://data.iscr.ac.cn/Article?id=03fac683049b3e224d298b402bf8a327
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The adult stem/progenitor cell maintenance in the prostate is regulated by a balance between BMP5 self-renewal signal and GATA3 dampening activity. Here we report that the transcription factor GATA3 controls basal stem/progenitor cell maintenance in the prostate by directly controling the expression of BMP5, a key effector of this activity.
提供机构:
mcgill university
创建时间:
2022-02-20
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