Effects of CDK8/19 Mediator Kinase inhibition by BI1347 and depletion by SNX7886 on gene expression in HEK293 cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE231891
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资源简介:
RNA-Seq analysis was carried out to investigate the effects of selective CDK8/19 inhibitor BI1347 and PROTAC degrader SNX7886 on gene expression in HEK293 cells (293-WT) or the CDK8/19 double-knockout (293-dKO) derivatives. 293-WT or 293-dKO cells were treated with 0.1% DMSO (vehicle control) or 200nM BI1347 or 200nM SNX7886 for 3 days (72 hours). Each treatment condition was done in biological triplicate or quadruplicate.
创建时间:
2023-08-21



