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Biomimetic Synthesis of Antimalarial Naphthoquinones

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NIAID Data Ecosystem2026-03-06 收录
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The total synthesis of naphthoquinone natural products isolated from the Bignoniaceae plant family is described. Pinnatal, isopinnatal, sterekunthals A and B, pyranokunthones A and B, and anthrakunthone have been prepared along the lines of a biosynthetic proposal involving pericyclic reactions as key steps. The first case of catalysis in oxa 6π electrocyclizations is reported.

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2016-05-06
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