The genomic landscape of Mongolian hepatocellular carcinoma

Mongolia has the highest reported incidence of (and mortality from) hepatocellular carcinoma (HCC) in the world. This is the first molecular study aiming to characterize the genomic landscape of Mongolian HCC. Paired tumor/non-tumor liver tissue samples from a cohort of 76 hepatocellular carcinoma patients undergoing surgery between 2015 and 2016 at the National Cancer Center of Mongolia were sequenced with RNA-Seq and Whole Exome Sequencing (WES). This submission consists of 140 RNA-seq samples from 70 HCC tumors and matched nontumor tissue. Due to patient privacy concerns, patient phenotype and WES data has been submitted to dbGaP under accession phs002000.v1.p1. Grant: ZIA BC010313 Funding: NCI Intramural Research Program of the Center for Cancer Research Title: Molecular signatures for liver cancer diagnosis and treatment stratification Grantee: Xin W. Wang Grant: ZIA BC010876 Funding: NCI Intramural Research Program of the Center for Cancer Research Title: The role of cancer stem cells in liver cancer heterogeneity and subtypes Grantee: Xin W. Wang Grant: ZIA BC010877 Funding: NCI Intramural Research Program of the Center for Cancer Research Title: The identification of human hepatocellular carcinoma metastasis genes Grantee: Xin W. Wang Grant: ZIA BC011870 Funding: NCI Intramural Research Program of the Center for Cancer Research Title: Liver Cancer Program Grantee: Xin W. Wang