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Oviductal expression data from wild type and Wt1 heterozygous mice

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Comparison of gene expression in wild type and Wt1 (Wilms tumor suppressor gene 1) heterozygous knockout mice. Background: in Wt1+/- mice (MF1 strain) litter sizes are significantly smaller than in wild type animals. In addition, we observe retarded embryonic development of pre-implantation embryos that are still within the oviduct. By gene expression analysis we want to elucidate the molecular basis for these phenomena. 3 wild type and 3 heterozygous RNA samples

野生型与Wt1(Wilms肿瘤抑制基因1,Wilms tumor suppressor gene 1)杂合敲除小鼠的基因表达对比分析。背景:Wt1+/-(MF1品系)小鼠的产仔数显著低于野生型个体。此外,我们观察到仍滞留于输卵管内的植入前胚胎存在发育迟缓现象。本研究旨在通过基因表达分析阐明上述现象的分子机制。本数据集共包含3份野生型及3份杂合敲除型RNA样本。

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