five

Ncf2

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rgd.mcw.edu2025-01-22 收录
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资源简介:
ENCODES a protein that exhibits small GTPase binding (ortholog); superoxide-generating NAD(P)H oxidase activity (ortholog); superoxide-generating NADPH oxidase activator activity (ortholog); INVOLVED IN cellular response to hormone stimulus; positive regulation of blood pressure; positive regulation of neuron apoptotic process; PARTICIPATES IN Leishmaniasis pathway; phagocytosis pathway; ASSOCIATED WITH decreased NAD(P)H oxidase activity; decreased susceptibility to hypertension; salt-sensitive hypertension; ASSOCIATED WITH Burns; Experimental Diabetes Mellitus; hypertension; FOUND IN acrosomal vesicle (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acetamide

编码一种表现小GTPase结合(同源)的蛋白质;产生超氧阴离子的NAD(P)H氧化酶活性(同源);产生超氧阴离子的NADPH氧化酶激活活性(同源);参与细胞对激素刺激的应答;正向调控血压;正向调控神经元凋亡过程;参与利什曼病通路;吞噬作用通路;与NAD(P)H氧化酶活性降低相关;降低对高血压的易感性;盐敏感性高血压;与烧伤、实验性糖尿病、高血压相关;存在于顶体囊泡(同源)、细胞质(同源)、细胞溶质(同源);与17β-雌二醇、2,3,7,8-四氯二苯并-对-二恶英、乙酰胺相互作用。
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