Down-regulation of N4-acetylcytidine modification in myeloid cells attenuates immunotherapy and exacerbates hepatocellular carcinoma progression

To resolve the patterns of TILs in HCC, we performed scRNA-seq on the TILs isolated from the three groups (P: control group, T: immunotherapy group, TR: immunotherapy plus REM group; n=2 per group) at two time points (1 w and 2 w) Comparative gene expression profiling analysis of single-cell RNA-seq data for the TILs isolated from tumor of mice hepatocellular carcinoma orthotopic transplantation model.