Mutation patterns in LPV/r failing C patients from Israel and South Africa.

The table lists all mutation patterns that appeared more than once in the combined dataset of 101 samples, 55 from South Africa (van Zyl et al.[33]) and 46 from Israel (this study). Fifty nine samples (58% of total) included 16 patterns. The actual frequency (number of times a pattern appeared in the dataset) and the calculated frequency (based on the overall frequencies of each mutation included in that pattern, assuming independence) for the most prevalent patterns are compared. p-values were calculated using Fisher's two- tailed Exact Test. IL – Israel; SA – South Africa.