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Crystal structure of Lysine Specific Demethylase 1 (LSD1) with CC-90011

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Protein Data Bank Japan2023-10-18 更新2026-03-21 收录
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Crystal structure of Lysine Specific Demethylase 1 (LSD1) with CC-90011 Descriptor: 4-[2-(4-aminopiperidin-1-yl)-5-(3-fluoro-4-methoxyphenyl)-1-methyl-6-oxo-1,6-dihydropyrimidin-4-yl]-2-fluorobenzonitrile, FLAVIN-ADENINE DINUCLEOTIDE, Lysine-specific histone demethylase 1A, ... Authors: Hosfield, D.J. Deposit date: 2020-03-11 Release date: 2020-10-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.93 Å) Cite: Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1). J.Med.Chem., 63, 2020
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2020-03-11
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