HOMA-IR PC vs logMetabolite—Univariate model—Analysis.

Includes all meta-analysis results for univariate model after filtering (see Methods). Metabolite: metabolite name, N_Samples: number of samples, N_Studies: number of cohorts that had data for the metabolite (up to 3), Beta_Fixed: effect size from fixed effects meta-analysis, SE_Fixed: standard error from fixed effects meta-analysis, Zvalue_Fixed: z-score from fixed effects meta-analysis, Pvalue_Fixed: p-value from fixed effects meta-analysis, Beta_Random: effect size from random effects meta-analysis, SE_Random: standard error from random effects meta-analysis, Zvalue_Random: z-score from random effects meta-analysis, Pvalue_Random: p-value from random effects meta-analysis, Q: Cochran q-test statistic, Q_df: Cochran q-test degrees of freedom, Q_Pvalue: Cochran q-test p-value, Tau2: tau-squared between-study variance, H: H-statistic, I2: I-squared statistic, WLM_GP1_Beta: Effect size within WLM, WLM_GP1_SE: standard error within WLM, WLM_GP1_Num: number of samples within WLM, StrridePD_Beta: effect size within STRRIDE-PD, StrridePD_SE: standard error within STRRIDE-PD, StrridePD_Num: Number of samples within STRRIDE-PD, CBD_Beta: effect size within CBD, CBD_SE: standard error within CBD, CBD_Num: number of samples within CBD, Method: LC-MS method used to measure metabolite, HMDB.ID…representative.ID.: HMDB ID for metabolite, super_class: HMDB metabolite taxonomy super class, class: HMDB metabolite taxonomy class, sub_class: HMDB metabolite taxonomy sub class, missingness: metabolite missingness rate, zeroness: metabolite rate of being zero value, CV: metabolite coefficient of variation, Pvalue_Adj_Fixed: FDR adjusted p-value from fixed effects meta-analysis, Pvalue_Adj_Random: FDR adjusted p-value from random effects meta-analysis. (XLSX)