Additional file 1: of Effects of PKM2 on global metabolic changes and prognosis in hepatocellular carcinoma: from gene expression to drug discovery

Table S1. Differentially expressed genes in high-PKM2 group. Table S2. Differentially expressed genes in low-PKM2 group. Table S3. Descriptive statistics of PKM2 and other clinical features grouped by hierarchical clustering. Table S4. Multivariate logistic regression between PKM2 and hierarchical clustering groups with adjusted covariates. Table S5. Details of gene set enrichment analysis in high-PKM2 vs. controls, low-PKM2 vs. controls and high-PKM2 vs. low-PKM2. Table S6. Correlation between PKM2 and metabolic genes in high-PKM2 group. Table S7. Correlation between PKM2 and metabolic genes in low-PKM2 group. Table S8. Survival analysis of up-regulated and PKM2-positively correlated metabolic genes. Table S9. Survival analysis of down-regulated and PKM2-negatively correlated metabolic genes. Table S10. Interaction of PKM2 and PKM2-uncorrelated metabolic genes on patients’ overall survival. Table S11. Transcriptional regulation relationships of key metabolic genes. Table S12. Information of key metabolic genes and drugs. Table S13. Predicted compounds that affect risk metabolic genes by L1000CDS2 web tools. (XLSX 794 kb)