Hi-reComb: Constructing recombination maps from bulk gamete Hi-C sequencing

Recombination is central to genetics and the evolution of sexually reproducing organisms. However, obtaining accurate estimates of recombination rates and of how they vary along chromosomes continues to be challenging. To advance our ability to estimate recombination rates, we present Hi-reComb, a new method and software for the estimation of recombination maps from bulk gamete chromosome conformation capture sequencing (Hi-C)., , , # Hi-reComb: Constructing recombination maps from bulk gamete Hi-C sequencing

Dataset DOI: [10.5061/dryad.4f4qrfjns](10.5061/dryad.4f4qrfjns)

## Description of the data and file structure

The file reconstructed_maps.tar.gz contains all the recombination maps generated for the above paper in a gzipped tar archive that, after unpacking, follows the file structure assumed by the analysis code available at [https://github.com/millanek/Hi-reComb_paper_analyses/](https://github.com/millanek/Hi-reComb_paper_analyses/).

#### File: reconstructed_maps.tar.gz

**Description:** The tar archive contains the following subfolders

* maps/simulated: These are the simulated maps underlying Fig. 2

- maps/reconstructed: These are the maps for Fig. 3

* maps/reconstructed/wBootstrap: These are the maps for Fig. 4

- maps/LD: These are the stickleback linkage disequilibrium (LD) -based maps underlying the comparisons in Fig. 5

* maps/reconstructed/wDepth: This file contains the effective depth data un...,