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³Cells-of-origin transcriptional memory governs self-renewal of MLL cancer stem cells². ³Cells-of-origin transcriptional memory governs self-renewal of MLL cancer stem cells²

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NIAID Data Ecosystem2026-03-09 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJEB9628
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From mice, strand-specific RNA-Seq of granulocyte-myeloid progenitors (GMP) and hematopoietic stem cells (HSC). Cancer stem cells (CSC) were created with MLL-ENL transfections using puromycin for both GMP and HSCs. Further knock-outs were created of β-catenin (Ctnnb1) and Hoxa9.
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2016-07-01
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