Influence of copy number alterations in gene deregulation in cervical carcinomas.

a21,034 genes were explored in all but four tumors (R062, R111, R116, R248) for changes in expression with HG 1.0 ST microarray. On average 1,673 of them were CN-altered (CN1/CN3) and 19,362 did not have copy number alterations (CN2). CN1 means genes with one copy deleted, CN2 means genes without CN alterations (2 copies), and CN3 means amplified genes with three or four copies.bCopy number altered genes according to data obtained with 500 K microarray.n = number of genes identified in the analysis of copy number with 500 K microarray that were also explored for gene expression with the HG 1.0 ST microarray.EX+ = Genes that were up- or down- regulated in tumors compared with the control sample.Samples R075 and R189 are ACC and R298 is ASCC, the rest are SCC.Samples labeled with an asterisk were excluded for the survival analysis.