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Role of IL-12 in Staphylococcus aureus-triggered arthritis and sepsis

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PubMed Central2000-11-03 更新2026-04-25 收录
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https://pmc.ncbi.nlm.nih.gov/articles/PMC17823/
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资源简介:
The present study demonstrates that endogenous production of IL-12 is crucial for survival in Staphylococcus aureus-induced arthritis in mice. Staphylococcal load is enhanced in several organs, because of lack of IL-12. This might be due to decreased production of IFN-γ in IL-12-deficient mice. Although IL-12-deficient mice were exposed to higher staphylococcal load, they demonstrated no increased severity of arthritis as compared with control animals.
提供机构:
BMC
创建时间:
2000-11-03
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