Molecular characterization of undiagnosed cases of congenital hemolytic anemia using a multigene next-generation sequencing panel

1To investigate molecular defects in 200 cases of unexplained congenital anemia with reference gene associated with red hemoglobinopathies, cell membrane protein disorder and rare red cell enzymopathies using next-generation sequencing.2. The systematic genotype-phenotype correlation will be undertaken in these patients to look for the association of gene defects on the clinical outcome of the patients.