Crystal structure of a constitutively active mutant of human IDH3 holoenzyme in apo form

Crystal structure of a constitutively active mutant of human IDH3 holoenzyme in apo form Descriptor: Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, Isocitrate dehydrogenase [NAD] subunit gamma, ... Authors: Sun, P, Chen, X, Ding, J. Deposit date: 2022-09-04 Release date: 2022-11-30 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (4.486 Å) Cite: Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022