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Gene expression changes of phenolphthalein-induced in renal cortex of rats

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This study is to develop a short term and highly accurate prediction method of renal carcinogenicity based on gene expression profile of rats administrated by carcinogens. We conducted 28 days-repeated dose experiments in male SD rats with phenolphthalein, and the gene expression profiles of renal cortex were analyzed using custom microarrays.

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