five

Mutant human thymidylate kinase complexed with TMP and APPNP

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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Mutant human thymidylate kinase complexed with TMP and APPNP Descriptor: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... Authors: Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reintein, J, Goody, R.S, Konrad, M, Schlichting, I. Deposit date: 2000-10-10 Release date: 2001-10-11 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Potentiating Azt Activation: Structures of Wildtype and Mutant Human Thymidylate Kinase Suggest Reasons for the Mutants' Improved Kinetics with the HIV Prodrug Metabolite Aztmp J.Mol.Biol., 304, 2000
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2000-10-10
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